Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB1 receptor following osteoarthritis
The highlights of the anandamide study are: Abstract Chronic pain is a complex, long-term illness that can lead to mood disorders, tension, and worry. Osteoarthritis (OA) is one of the primary causes of chronic suffering in adults and elderly individuals. The hippocampus’s neural circuitry, including monoamine dopamine and serotonin levels, has been shown to play …